Ligand Pharmaceuticals Incorporated (LGND) fair value: what the stock is really worth
As of Nov 6, 2026: fair value (intrinsic value) of Ligand Pharmaceuticals Incorporated stock $108, price $306, that is 64.6% below the price, quality 52 out of 100. Rating: strongly overvalued. Calculated from audited financials with 22 of our 26 valuation models and 37 quality factors, updated daily.
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Ligand Pharmaceuticals Incorporated
LGND · USOur calculation puts a fair price 65% below what the stock costs today.
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Price vs Fair Value
White line = price, green steps = our fair value per fiscal year. As of Nov 8, 2026.
How to read this chart
60‑month range $46.49 – $322.75 · fair‑value band $70.60 – $216.14 · the $306.20 price screens above the $108.46 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). As of Nov 8, 2026.
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Company profile
Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, develops and licenses biopharmaceutical assets worldwide.
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It offers Pradefovir, Posaconazole, Voriconazole, CAPVAXIVE, NOXAFIL, MenFive, and ZELSUVMI for infectious disease; EVOMELA and KYPROLIS for multiple myeloma; FILSPARI for the treatment of immunoglobulin a nephropathy; PNEUMOSIL, a pneumococcal conjugate vaccine to help fight against pneumococcal pneumonia in children; and QARZIBA to treat neuroblastoma.
The company also provides Teriparatide injection product for osteoporosis; RYLAZE, a recombinant erwinia asparaginase for acute lymphoblastic leukemia or lymphoblastic lymphoma in adult and pediatric patients; TZIELD, a CD3-directed antibody indicated to delay the onset of Stage 3 type 1 diabetes in adults and children aged 8 years and older with Stage 2 T1D; and VAXNEUVANCE for the prevention of invasive disease caused by streptococcus pneumoniae serotypes.
In addition, it offers Duavee for menopause; Frovatriptan to treat Neurology; FYCOMPA and SESQUIENT for CNS; MEKINIST for cardiology; Nexterone, a captisol-enabled formulation of amiodarone; VEKLURY, an antiviral treatment for COVID-19; and Viviant for osteoporosis.
Further, the company develops ACLX-002, Ciforadenant, UGN-301, Viright, MB07133, BOT/BAL, and Lasofoxifene for oncology; Ensifentrine for respiratory disease; QTORIN for rare disease; Sparsentan for kidney disease; VK2809 for hepatology; ANEB-001 for acute cannabinoid intoxication; Reproxalap for opthamology; VK0214 for Rare Disease; and VK5211 for musculoskeletal disorder.
The company was incorporated in 1987 and is based in Jupiter, Florida.
Stock analysis
Ligand Pharmaceuticals Incorporated (LGND) currently trades at $306.20, while our model-based Fair Value estimate is $108.46, 65% below the price, so the stock looks overvalued today.
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Valuation
Bull case: the Growth Earnings group reads highest at a median of $209.81 per share, and 0 of the 22 models we run sit above the $306.20 price.
Bear case: the Asset-Based group reads lowest at $14.49, and 22 of the 22 models stay below the price. Data coverage for this calculation is medium.
Scenario range: $70.60 (bear) to $216.14 (bull), the price of $306.20 sits above it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.
Quality & growth
The Quality Score stands at 52/100 (solid quality), in the Healthcare sector.
Mixed Growth: Revenue is growing, but margins or cash flow do not fully confirm the trend.
Ligand Pharmaceuticals Incorporated reported revenue of $268M in FY2025 versus $242M in FY2021, a compound +2.6%/yr. Reported net income was $124M in FY2025, compounding +21.5%/yr from FY2021.
Key figures
Market cap $6.7B Mid · P/E ratio 32.3 · P/S ratio 15.0 · EPS (TTM) $9.49 · Net margin 46.4% · Return on equity 5.4% · Return on assets (EBIT) 2.1% (5-year average) · Operating margin −12.1%.
Competitive moat
Our AI-assisted moat analysis scores the competitive advantage at 43 out of 100 (low confidence).
What moves the price
The share trades about 5% below its 52-week high and 69% above its 52-week low, currently above its 200-day average.
For context, the median of 10 Healthcare peers we cover trades at 10% fair-value upside, at −65%, LGND screens richer than that median.
Fair Value models
All 22 models by family
Quality Score breakdown
It rates the business: profits, how they develop, real cash, balance sheet, investing and share count.
Insider trades
In the last 6 months, 8 officers or directors sold shares worth $26.2M and none bought.
- SaleJason AryehDirector3× since Jun 10, 2026: 7,393 shares, avg. $272.74$2.0MNov 4, 2026
- SaleAndrew ReardonCLO & Secretary9× since Mar 4, 2026: 45,000 shares, avg. $263.51$11.9MNov 2, 202610b5-1 plan
- SaleMartine ZimmermannDirector1,200 shares at $285.00$342,000Sep 10, 2026
- SaleJason HaasDirector2× since Jun 12, 2026: 13,599 shares, avg. $275.12$3.7MAug 12, 2026
- SaleOctavio EspinozaChief Financial Officer4× since Dec 12, 2025: 49,925 shares, avg. $261.03$13.0MAug 12, 2026
- SaleStephen L SabbaDirector3× since Mar 3, 2026: 5,179 shares, avg. $224.47$1.2MJun 16, 2026
- SaleJohn L LamattinaDirector2× since Mar 6, 2026: 6,752 shares, avg. $234.84$1.6MJun 10, 2026
- SaleJohn W KozarichDirector6× since Dec 1, 2025: 4,836 shares, avg. $211.46$1.0MMay 13, 202610b5-1 plan
Plus 21 other filings such as grants, option exercises or tax withholding. They are not market purchases or sales.
Sales are often planned (taxes, diversification, 10b5-1 plans). Purchases with their own money are seen as the stronger sign. For information only: not part of the quality score or Fair Value.
Source: SEC Form 4, as of Nov 6, 2026. All filings at the SEC ↗
Revenue & earnings trend
Growth Forecast
Earlier news
- Ligand Pharmaceuticals Sees Strong Royalty Growth Ahead of Investor Day, Oppenheimer Says
- Ligand Pharmaceuticals (LGND) Stock Price Ignores Q3 Earnings Losses And Royalty Strength
- Ligand raises 2026 adjusted EPS guidance to $9.50-$9.75 while targeting ~$200M annual capital deployment
- Ligand: Q3 Earnings Snapshot
Compare Ligand Pharmaceuticals Incorporated with another stock
Price, fair value, quality and upside side by side.
Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 558 stocks
Valuation Multiplesvs Biotechnology median · lower = cheaper
Strength profile in five axes (Snowflake)
VALUE 0: the price sits above our fair-value range.
Context: sector, industry, market
- Is the Health Care sector expensive or cheap?
- P/E, EV/EBITDA and margins by industry (reference tables)
- P/B ratio by industry
- Net margin by industry
- Piotroski F-Score screener with fair value
- Undervalued stocks: US Stocks
- Valuation of the USA market
Values & ESG
Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.
Similar stocks
10 more Biotechnology stocks, each showing price versus our Fair Value estimate.
| Stock | Price | Fair Value | vs Fair Value | Compare |
|---|---|---|---|---|
| Incyte Corporation INCY | $119.65 | $199.23 | +67% | vs LGND |
| Regeneron Pharmaceuticals, Inc REGN | $904.35 | $1,275 | +41% | vs LGND |
| Vertex Pharmaceuticals Incorporated VRTX | $547.09 | $601.80 | +10% | vs LGND |
| Samsung Biologics Co 207940 | 1,516,000 KRW | 1,667,600 KRW | +10% | vs LGND |
| Genmab A/S GMAB | kr 3,527 | kr 3,880 | +10% | vs LGND |
| WuXi Biologics (Cayman) Inc 2269 | HK$47.62 | HK$52.38 | +10% | vs LGND |
| argenx SE ARGX | $927.21 | $908.40 | −2% | vs LGND |
| CSL Limited CSL | A$200.77 | A$183.04 | −9% | vs LGND |
| Celltrion, Inc 068270 | 211,000 KRW | 74,945 KRW | −64% | vs LGND |
| Royalty Pharma plc RPRX | $67.30 | $19.01 | −72% | vs LGND |
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Key figures of Ligand Pharmaceuticals Incorporated
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