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Ligand Pharmaceuticals Incorporated (LGND) Fair Value & Analysis

Healthcare · US · Market cap $6.5B

LP Ligand Pharmaceuticals Incorporated logo Ligand Pharmaceuticals Incorporated LGND · US
Price$293.15
Fair Value$47.37
Upside-83.8%
Quality55/100
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Mixed Growth
Highly profitable · 56.0% net margin
Low debt · generates free cash flow
Mixed vs. peers (6/14)
Wide moat 74/100
Evidence: High Range $29.84 – $109.48 Share as image

Fair value as of: Jul 11, 2026

From 26 valuation models · updated 29 days ago

Share price −6.9% over the past month.

A solid business, but screening 84% overvalued on our models.

What matters now

  • The price sits above even our optimistic bull case ($109.48). The favourable scenario is already priced in.
  • The model range is unusually wide ($29.84 to $109.48). The outcome hinges heavily on assumptions, so read the point estimate with caution.
  • Solid but not exceptional quality (55/100) and above fair value, neither a clear bargain nor a standout compounder.
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Price vs Fair Value (5 years)

$322.61 $46.49 Fair Value $47.37 May 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 11, 2026.

How to read this chart

60‑month range $46.49 – $322.61 · fair‑value band $29.84 – $109.48 · the $293.15 price screens above the $47.37 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Jul 11, 2026.

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Analysis

Ligand Pharmaceuticals Incorporated (LGND) currently trades at $293.15, while our model-based Fair Value estimate is $47.37, implying the stock looks roughly 83.8% overvalued today. The Quality Score stands at 55/100 (solid quality), in the Healthcare sector. Bear case: priced above our estimate, the market already discounts strong expectations. Bull case: above-average quality can justify a premium, the entry price still matters most (evidence: high).

Over the trailing twelve months, Ligand Pharmaceuticals Incorporated generated revenue of $274M at a net margin of 56.0%. Revenue grew 14.1% year over year. It earns a return on equity of 17.1%. Net debt stands at $277M. Fundamentals as of Jul 11, 2026

Our scenario range runs from $29.84 (bear case) to $109.48 (bull case); at $293.15, the current price sits above that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades near its 52-week high and 183% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -43% fair-value upside, at -84%, LGND screens richer than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model BearBaseBull Evidence
Highest evidence
Growth DCF $20.51 $51.99 $108.90 80
Residual Income $46.40 $55.49 $129.03 76
Rev-Margin DCF $12.70 $35.64 $69.38 74
All 26 models by family
DCF Models
FCF DCF $22.09 $46.22 $111.53 38
Owner Earnings $102.80 $239.28 $510.91 31
5Y Revenue Exit $12.70 $33.80 $71.68 39
5Y EBITDA Exit $26.65 $64.37 $128.44 41
5Y P/E Exit $66.87 $163.55 $288.14 38
10Y Revenue Exit $14.62 $39.78 $71.66 36
10Y EBITDA Exit $25.00 $65.02 $136.91 37
10Y P/E Exit $52.52 $137.76 $285.33 35
Earnings-Based
Graham-Dodd $42.23 $285.87 $400.66 54
Lynch FV $83.85 $119.79 $155.73 50
PEG = 1.0 $83.85 $119.79 $155.73 46
EPV $0.3200 59
Dividend Discount
Gordon GGM $2.19 $4.37 $6.62 70
DDM Multi-Stage $2.19 $3.78 $4.61 61
Multiples
P/E Multiple $102.46 $136.62 $170.77 63
P/S Multiple $35.11 $46.82 $58.52 58
P/B Multiple $79.18 $105.57 $131.96 55
EV/EBIT $16.49 $26.50 $36.51 53
EV/EBITDA $29.91 $44.39 $58.87 54
EV/Revenue $7.90 $17.08 $26.27 43
Asset-Based
NCAV (Graham) $25.38 $34.01 $50.76 50
Growth DCF
Growth DCF $20.51 $51.99 $108.90 80
Rev-Margin DCF $12.70 $35.64 $69.38 74
Economic Profit
Residual Income $46.40 $55.49 $129.03 76
ROIC Compounder $0.3200 72
Growth Earnings
Growth-Adj P/E $118.42 $169.17 $219.92 68

Widest divergence: Growth Earnings ($169.17) versus Dividend Discount ($3.78). Highest evidence: Growth DCF (80).

Key figures & financial health

Revenue (TTM) $274M
Revenue growth (YoY) +14.1%
Net margin 56.0%
Return on equity 17.1%
Free cash flow $48.9M FY2025
P/E ratio 41.0
More key figures
Operating margin 33.6%
EPS (TTM) $7.87
EPS growth (YoY) +103%
Net debt $277M FY2025

Figures from reported company fundamentals · as of Jul 11, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 55/100

Of which business quality 56 · Market factors (momentum, volatility) 82

Profitability 48
Margins and returns on capital today
Quality Growth 88
Are margins and returns improving?
Cashflow 61
Earnings quality: real cash, not paper profit
Fin. Strength 82
Balance sheet, leverage, solvency risk
Investment 34
Disciplined investing over empire-building
Low Volatility 58
Calm price path (market factor)
Momentum 93
Price trend over the last 3–12 months (market factor)
52W Momentum 92
Distance to the 52-week high (market factor)
Net Issuance 8
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, develops and licenses biopharmaceutical assets worldwide.

Full company description

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, develops and licenses biopharmaceutical assets worldwide. It offers Pradefovir, Posaconazole, Voriconazole, CAPVAXIVE, NOXAFIL, MenFive, and ZELSUVMI for infectious disease; EVOMELA and KYPROLIS for multiple myeloma; FILSPARI for the treatment of immunoglobulin a nephropathy; PNEUMOSIL, a pneumococcal conjugate vaccine to help fight against pneumococcal pneumonia in children; and QARZIBA to treat neuroblastoma. The company also provides Teriparatide injection product for osteoporosis; RYLAZE, a recombinant erwinia asparaginase for acute lymphoblastic leukemia or lymphoblastic lymphoma in adult and pediatric patients; TZIELD, a CD3-directed antibody indicated to delay the onset of Stage 3 type 1 diabetes in adults and children aged 8 years and older with Stage 2 T1D; and VAXNEUVANCE for the prevention of invasive disease caused by streptococcus pneumoniae serotypes. In addition, it offers Duavee for menopause; Frovatriptan to treat Neurology; FYCOMPA and SESQUIENT for CNS; MEKINIST for cardiology; Nexterone, a captisol-enabled formulation of amiodarone; VEKLURY, an antiviral treatment for COVID-19; and Viviant for osteoporosis. Further, the company develops ACLX-002, Ciforadenant, UGN-301, Viright, MB07133, BOT/BAL, and Lasofoxifene for oncology; Ensifentrine for respiratory disease; QTORIN for rare disease; Sparsentan for kidney disease; VK2809 for hepatology; ANEB-001 for acute cannabinoid intoxication; Reproxalap for opthamology; VK0214 for Rare Disease; and VK5211 for musculoskeletal disorder. The company was incorporated in 1987 and is based in Jupiter, Florida.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

Ligand Pharmaceuticals Incorporated reported revenue of $268M in FY2025 versus $242M in FY2021, a compound +2.6%/yr. Reported net income was $124M in FY2025, compounding +21.5%/yr from FY2021.

Growth Quality 83/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$268M
Latest YoY
+60.4%
Avg. growth/yr (3Y)
+11.0%
Avg. growth/yr (5Y)
+10.4%
Avg. growth/yr (31Y)
+10.2%
Revenue +2.6%/yr
FY21 $242M
FY22 $196M
FY23 $131M
FY24 $167M
FY25 $268M
Net income +21.5%/yr
FY21 $57.1M
FY22 −$33.4M
FY23 $52.2M
FY24 −$4.0M
FY25 $124M

LGND screens 84% overvalued. Compare with Vertex Pharmaceuticals Incorporated →

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Cite: Fair Value Calculator (2026). "Ligand Pharmaceuticals Incorporated Fair Value". https://www.fairvalue-calculator.com/stock/LGND

Earlier news

External third-party headlines (Yahoo Finance, Reuters and others), not an editorial selection.

Peer Group

Biotechnology · 603 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 55 · Above median
Fair Value upside −84% · Bottom 25%
Return on equity (TTM) 17% · Top 25%
Return on assets 5% · Top 25%
Net margin (TTM) 56% · Top 25%
Operating margin (TTM) 34% · Top 25%
Revenue growth 14% · Above median
Debt / equity 0.44× · Higher than 75% of peers

Valuation Multiples vs Biotechnology median · lower = cheaper

P/E (TTM) 41.0× · Pricier than median
P/B 6.36× · Pricier than 75% of peers
P/S (TTM) 23.56× · Pricier than 75% of peers
P/FCF 132.2× · Pricier than 75% of peers
EV/EBITDA 50.1× · Pricier than 75% of peers
PEG 1.53× · Pricier than median

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 0 · sector 0
FUTURE 71 · sector 0
PAST 69 · sector 0
HEALTH 78 · sector 97
DIVIDEND 0 · sector 23

VALUE 0: the price sits above our fair-value range.

Insider activity: 40/100

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Jul 11, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $486.03 $278.78 -43%
Regeneron Pharmaceuticals, Inc REGN $664.45 $594.40 -11%
Samsung Biologics Co 207940 1,368,000 KRW 1,091,384 KRW -20%
Celltrion, Inc 068270 175,800 KRW 76,325 KRW -57%
WuXi Biologics (Cayman) Inc 2269 HK$39.54 HK$30.42 -23%
Innovent Biologics, Inc 1801 HK$86.70 HK$19.66 -77%
Sino Biopharmaceutical Limited 1177 HK$5.26 HK$3.36 -36%
ALTEOGEN Inc 196170 276,500 KRW 44,444 KRW -84%
RemeGen Co 688331 ¥134.02 ¥26.99 -80%
Biocon Limited BIOCON ₹440.70 ₹57.36 -87%

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Frequently asked questions

Is Ligand Pharmaceuticals Incorporated (LGND) overvalued or undervalued?
As of Jul 11, 2026, our model estimates a fair value of $47.37 versus a price of $293.15, about −84% (overvalued).
What is the fair value of LGND?
Our model-based fair value for Ligand Pharmaceuticals Incorporated is $47.37 (as of Jul 11, 2026), built from audited fundamentals. The current price is $293.15.
What is the quality score of LGND?
Ligand Pharmaceuticals Incorporated has a Quality Score of 55/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of Ligand Pharmaceuticals Incorporated (LGND)?
Ligand Pharmaceuticals Incorporated reported trailing-twelve-month revenue of about $274M (latest available figure, as of Jul 11, 2026).
What is the net profit margin of LGND?
The net profit margin of Ligand Pharmaceuticals Incorporated is about 56.0%, meaning it keeps roughly 56.0% of revenue as net income. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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