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MeiraGTx Holdings PLC (MGTX) fair value: what the stock is really worth

We calculate from audited financials what MeiraGTx Holdings PLC is really worth. The fair value tells you whether the price is too high or too low, the quality score (0 to 100) how solid the business behind it is. 26 models, 37 quality factors, updated daily.

Valuation from Jun 23, 2026. With the latest figures (losses, negative cash flow), a fair value can no longer be calculated.
  1. Fair value above price? No
  2. Good quality? No
  3. Add to watchlist

Healthcare · US · ISIN KYG596651029

MH MeiraGTx Holdings PLC logo Thin data Jun 23, 2026

MeiraGTx Holdings PLC

MGTX · US

Weakest SetupStrongly overvalued and low quality.

!Fair value $2.62 · Strongly overvalued (−78%)
!Quality 35/100
!Mixed Growth (revenue 5y +39.2 %/yr)
!Loss-making · -151.1% net margin (TTM)
!Negative equity (buybacks among others) · negative free cash flow
!Trails peers (0/6)
!Narrow moat 11/100
!Insider activity 42/100
!Evidence only low, so the estimate is less certain
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26 valuation models 8 families, DCF to NCAV 37 quality factors margins, balance sheet, cashflow, debt 6 AI factors moat, what no ratio measures 2,000+ data points verified, per stock, median

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Price vs Fair Value

$23.74 $3.60 Fair Value $2.62 Jun 2021 Sep 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jun 23, 2026.

How to read this chart

60‑month range $3.60 – $23.74 · fair‑value band $1.96 – $3.27 · the $11.75 price screens above the $2.62 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Jun 23, 2026.

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Company profile

MeiraGTx Holdings plc, a clinical-stage genetic medicines company, focusing on developing treatments for patients with serious diseases. The company develops various therapies for ocular diseases, including inherited retinal diseases and large degenerative ocular diseases; neurodegenerative diseases; and xerostomia.

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MeiraGTx Holdings plc, a clinical-stage genetic medicines company, focusing on developing treatments for patients with serious diseases. The company develops various therapies for ocular diseases, including inherited retinal diseases and large degenerative ocular diseases; neurodegenerative diseases; and xerostomia. It is also develops AAV-AQP1 for radiation-induced grade 2/3 radiation-induced xerostomia, as well as for Sjogren's syndrome; AAV-GAD in Phase 2 trial for Parkinson's disease; AAV-RPE65 in Phase 2 trial for RPE65-associated retinal dystrophy; and AAV-CNGB3 and AAV-CNGA3, which are both in Phase ½ clinical trial for achromatopsia, as well as offers AAV-AIPL1 for Leber congenital amaurosis (LCA) 4. In addition, the company's products under preclinical development include AAV-RDH12 for retinol dehydrogenase 12 mutation-associated retinal dystrophy; AAV-BBS10 for Bardet-Biedl syndrome (BBS) due to BBS10 mutations; AAV-RetGC for LCA type 1; and AAV-UPF1 for amyotrophic lateral sclerosis, as well as programs for Alzheimer's disease, and wet and dry neovascular age related macular degeneration. Further, it provides riboswitch platform for the delivery of metabolic peptides; and cell therapies for oncology, autoimmune disease, and long term intractable pain. The company has collaborations with Johnson & Johnson Innovative Medicine for the research, development, and commercialization of gene therapies for the treatment of inherited retinal disease; and Hologen Limited for the research, development, manufacture, and commercialization of AAV-GAD investigational gene therapy for the treatment of Parkinson's disease, AAV-BDNF investigational gene therapy for genetic obesity disorders, and other genetic medicines to the central nervous system. MeiraGTx Holdings plc was founded in 2015 and is based in New York, New York.

Stock analysis

MeiraGTx Holdings PLC (MGTX) currently trades at $11.75, while our model-based Fair Value estimate is $2.62, implying the stock looks roughly 348.8% overvalued today.

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Valuation

How firm this estimate is: it rests on 3 models at a data quality of 95/100, which puts the evidence level at low.

Scenario range: $1.96 (bear) to $3.27 (bull), the price of $11.75 sits above it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.

Quality & growth

The Quality Score stands at 35/100 (below-average quality), in the Healthcare sector.

Mixed Growth: Revenue is growing, but margins or cash flow do not fully confirm the trend.

MeiraGTx Holdings PLC reported revenue of $81.4M in FY2025 versus $37.7M in FY2021, a compound +21.2%/yr. Reported net income was −$114M in FY2025.

Key figures

Market cap $1.0B · P/S ratio 13.1 · EPS (TTM) $−1.48 · Net margin −140% · Return on equity −368% · Return on assets (EBIT) −41.1% · Operating margin −13,931% · Revenue (TTM) $79.8M.

Competitive moat

Our AI-assisted moat analysis scores the competitive advantage at 30 out of 100 (medium confidence).

What moves the price

The share trades about 22% below its 52-week high and 68% above its 52-week low, currently above its 200-day average.

For context, the median of 10 Healthcare peers we cover trades at −5% fair-value upside, at −78%, MGTX screens richer than that median.

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Quality Score breakdown

Overall quality 35/100

Of which business quality 34 · Market factors (momentum, volatility) 62

Profitability 18
Margins and returns on capital today
Quality Growth 100
Are margins and returns improving?
Cashflow 0
Earnings quality: real cash, not paper profit
Fin. Strength 30
Balance sheet, leverage, solvency risk
Investment 95
Disciplined investing over empire-building
Low Volatility 22
Calm price path (market factor)
Momentum 84
Price trend over the last 3–12 months (market factor)
52W Momentum 72
Distance to the 52-week high (market factor)
Net Issuance 0
Share count: buybacks or dilution?

Open the full quality analysis →

Revenue & earnings trend

Growth Quality ⓘGrowth is valuable only when reinvestment earns attractive returns (Aswath Damodaran): sustainable growth depends on return on capital, reinvestment and efficiency. Basis: total company revenue over the periods shown on the cards (3Y/5Y/all years), not per share, so a merger can show up as a growth jump; per-share earnings growth is in the value-creation card. 32/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Revenue growth 1 year
+144.6%
Revenue growth 3 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+72.3%
Revenue growth 5 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+39.2%
Start year 2020 (pandemic)
Revenue growth 6 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+35.3%
Profit margin (trend) ⓘOperating margin then vs now, from reported annual statements. A falling margin after a boom year is the classic peak-earnings signal: the growth rate then leans on an inflated base.
−401.9% (2020) → −130.2% (2025)
What shareholders gained per year ⓘWe only publish this rate when it is defensible. Reason: fiscal 2025 is a loss year, no rate is defined from a loss
not computed

MGTX screens 349% overvalued. Compare with Vertex Pharmaceuticals Incorporated →

Earlier news

News mood ⓘNews mood, the average tone of recent news (74 articles), rated against how stocks are usually covered. 🚀 Hype = unusually upbeat · 🙂 Positive = above average · 😐 Neutral = typical · 🙁 Negative = below average · 😨 Very negative = unusually downbeat. It reflects the tone of coverage, not our valuation. Positive
Recent news coverage is more positive than average.

Compare MeiraGTx Holdings PLC with another stock

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Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 651 stocks

Beats the industry median on 0/6 measures
Overall it trails its industry peers.
Valuation
Quality Score 35 · Below median
Fair Value upside −78% · Bottom 25%
Profitability
Return on equity (TTM) Negative equity ⓘThe company's equity is below zero, for example after large share buybacks. A ratio to negative equity has no meaning, so we show no number here and do not rank it against the peer group.
Return on assets −28% · Below median
Net margin (TTM) −151% · Bottom 25%
Growth and dividend
Revenue growth −85% · Bottom 25%
Balance sheet
Debt / equity Negative equity ⓘThe company's equity is below zero, for example after large share buybacks. A ratio to negative equity has no meaning, so we show no number here and do not rank it against the peer group.

Valuation Multiplesvs Biotechnology median · lower = cheaper

P/B Negative equity ⓘThe company's equity is below zero, for example after large share buybacks. A ratio to negative equity has no meaning, so we show no number here and do not rank it against the peer group.
P/S (TTM) 13.14× · Priciest 25%

Context: sector, industry, market

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate.

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $514.99 $566.49 +10%
Regeneron Pharmaceuticals, Inc REGN $803.90 $1,252 +56%
argenx SE ARGX $963.79 $918.60 −5%
Samsung Biologics Co 207940 1,366,000 KRW 1,502,600 KRW +10%
CSL Limited CSL A$179.24 A$197.16 +10%
Alnylam Pharmaceuticals, Inc ALNY $251.65 $218.36 −13%
Royalty Pharma plc RPRX $58.52 $24.22 −59%
BeOne Medicines AG 6160 HK$218.20 HK$169.72 −22%
Celltrion, Inc 068270 177,400 KRW 74,519 KRW −58%
BioNTech SE BNTX $100.87 $63.62 −37%

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MeiraGTx Holdings PLC · Fair Value
$2.62 −349%Fair Value
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Cite: Fair Value Calculator (2026). "MeiraGTx Holdings PLC Fair Value". https://www.fairvalue-calculator.com/stock/MGTX

Frequently asked questions

Is MeiraGTx Holdings PLC (MGTX) overvalued or undervalued?
As of Jun 23, 2026, our model estimates a fair value of $2.62 versus a price of $11.75, about −78% upside (overvalued).
What is the fair value of MGTX?
Our model-based fair value for MeiraGTx Holdings PLC is $2.62 (as of Jun 23, 2026), built from audited fundamentals. The current price: $11.75.
What is the quality score of MGTX?
MeiraGTx Holdings PLC has a Quality Score of 35/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the price target for MeiraGTx Holdings PLC (MGTX)?
Our model-based price target is the fair value of $2.62 (as of Jun 23, 2026) from 3 valuation models. Cautious scenario $1.96, optimistic scenario $3.27. It is a calculation from audited fundamentals, not an analyst target.
What is the MeiraGTx Holdings PLC stock forecast for 2026?
Our models put fair value at $2.62, about −78% upside versus a price of $11.75 (overvalued). Cautious scenario $1.96, optimistic scenario $3.27. The calculation is refreshed regularly with new filings.
What is the revenue of MeiraGTx Holdings PLC (MGTX)?
MeiraGTx Holdings PLC reported trailing-twelve-month revenue of about $79.8M (latest available figure, as of Jun 23, 2026).
What is the intrinsic value of MeiraGTx Holdings PLC (MGTX)?
Intrinsic value and fair value mean the same thing: what the business is worth on its numbers, independent of the share price. For MeiraGTx Holdings PLC it is $2.62 per share (as of Jun 23, 2026), against a price of $11.75. It is the blended result of 3 valuation models (cash flow, earnings, asset, dividend).
Is MeiraGTx Holdings PLC stock overvalued or undervalued in 2026?
As of Jun 23, 2026, MGTX trades above its calculated fair value: price $11.75, fair value $2.62, a gap of about −78% (overvalued). The calculation is refreshed with each new quarterly report, so the verdict can change during the year.
Is fair value the same as the market price of MGTX?
No. The price is what the market pays today ($11.75); the fair value is what the company's own numbers justify ($2.62). For MeiraGTx Holdings PLC the two are $9.13 per share apart. That gap is exactly why we show both numbers side by side.
How much is MeiraGTx Holdings PLC worth?
The market values MeiraGTx Holdings PLC at about $1.0B (market capitalisation, as of Jun 23, 2026). Per share that is $11.75; our models calculate a fair value of $2.62 per share.
What do the bullish and bearish scenarios say about MGTX?
Our models span a range for MeiraGTx Holdings PLC: cautious scenario $1.96, base $2.62, optimistic $3.27 per share (as of Jun 23, 2026, price $11.75). The range comes from different growth and margin assumptions, not from analyst opinions.
How solid is the balance sheet of MeiraGTx Holdings PLC (MGTX)?
Balance-sheet figures for MeiraGTx Holdings PLC (as of Jun 23, 2026): negative equity, so no return on equity and no debt-to-equity ratio. They feed the Quality Score of 35/100, which measures business quality independently of the share price.
How far is MGTX from its 52-week high?
MeiraGTx Holdings PLC trades at $11.75, about 22% below its 52-week high of $14.97 and 68% above the low of $6.99 (as of Sep 23, 2026). Distance from the high says nothing about value: that is what the fair value of $2.62 is for.
Which stocks are comparable to MeiraGTx Holdings PLC?
From the same area (Healthcare) we also value Vertex Pharmaceuticals Incorporated, Regeneron Pharmaceuticals, Inc, argenx SE, Samsung Biologics Co, among others. Each of them has its own fair-value calculation on this site using the same models, so the comparison is like for like.
Is MeiraGTx Holdings PLC stock attractive at the current price?
The data as of Jun 23, 2026: price $11.75, calculated fair value $2.62 (−78%), Quality Score 35/100, from 3 models. Whether that fits your horizon and risk tolerance is your call. We provide the calculation, not investment advice.
How is the fair value of MGTX calculated?
We run MeiraGTx Holdings PLC through 3 models from four families: discounted cash flow, earnings models, asset and balance-sheet models, and dividend models. Every model gets the same audited fundamentals; the result is the weighted average of $2.62, with the spread shown as a cautious and an optimistic scenario.
Is it still worth investing in stocks now?
The global stock market currently sits 14.1 % above its aggregate fair value. MeiraGTx Holdings PLC itself currently trades above fair value. An expensive market is no reason to stay out and no reason to buy everything at once: keep a broad savings plan running, buy single stocks only with money you can do without, and hold part of your money liquid while the market is high. The full picture including sectors is on is it worth investing now.
What is the share price of MeiraGTx Holdings PLC (MGTX)?
The closing price on Sep 23, 2026 was $11.75. Our model-based fair value is $2.62, about −78% upside (overvalued). We carry closing prices from our data provider, not a live tick.
What should I pay attention to with MeiraGTx Holdings PLC right now?
The price sits above even our optimistic bull case ($3.27). The favourable scenario is already priced in. Weak quality (35/100) and above fair value at the same time, the margin of safety is missing on both counts. The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution.

Key figures of MeiraGTx Holdings PLC

How large is the market capitalisation of MeiraGTx Holdings PLC (MGTX)?
The market capitalisation of MeiraGTx Holdings PLC is $1.0B. The stock-market value of the whole company: share price times number of shares. It is what the market asks for the entire business today.
What is the P/S ratio of MeiraGTx Holdings PLC (MGTX)?
The price-to-sales ratio of MeiraGTx Holdings PLC is 13.1 (last twelve months). Price to sales: market value relative to yearly revenue. Useful when profit is thin or distorted.
What are the earnings per share of MeiraGTx Holdings PLC (MGTX)?
Earnings per share at MeiraGTx Holdings PLC are $−1.48. Earnings per share over the last twelve months: total profit spread across every single share.
What is the net margin of MeiraGTx Holdings PLC (MGTX)?
The net margin of MeiraGTx Holdings PLC is −140% (fiscal year 2025). How much of every unit of revenue ends up as profit. 10% means 10 cents of profit per dollar of sales.
What is the return on equity of MeiraGTx Holdings PLC (MGTX)?
The return on equity (ROE) of MeiraGTx Holdings PLC is −368% (last twelve months). Profit relative to shareholders' equity, how efficiently the company works with its owners' money.
What is the EBIT return on assets of MeiraGTx Holdings PLC (MGTX)?
On an EBIT basis the return on assets of MeiraGTx Holdings PLC is −41.1% (avg 5y). Operating profit (EBIT) relative to everything the company owns, as a multi-year average. It describes the business model rather than one good or bad year.
What is the operating margin of MeiraGTx Holdings PLC (MGTX)?
The operating margin of MeiraGTx Holdings PLC is −13,931% (last twelve months). Profit from the core business (before interest and taxes) relative to revenue.
How fast is revenue growing at MeiraGTx Holdings PLC (MGTX)?
Revenue at MeiraGTx Holdings PLC is growing −84.8% versus a year earlier (3y avg +72.3%). How much revenue grew versus a year earlier (YoY). The 3-year average next to it puts the single year in context.
How much free cash flow does MeiraGTx Holdings PLC (MGTX) generate?
The free cash flow of MeiraGTx Holdings PLC is −$50.2M (fiscal year 2025). The cash truly left after running and investing in the business, this is what pays dividends and buybacks.
How much net debt does MeiraGTx Holdings PLC (MGTX) carry?
The net debt of MeiraGTx Holdings PLC is $22.8M (fiscal year 2025). Debt minus cash on hand. The note shows how many years of free cash flow could in theory pay it off.
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